This product is a 110 kDa native human C1 Inhibitor protein isolated from normal human serum. It is availible for ELISA, Functional Assays.
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Specie Reactivity | Human |
Target | C1 Inhibitor |
Molecule Mass | 110 kDa |
Purity | >95% determined by SDS-PAGE |
Endotoxin | <1.0EU per 1µg (determined by the LAL method) |
Formulation | 10 mM sodium phosphate, 145 mM NaCl, pH 7.3 |
Applications | ELISA; Functional Assays |
Product Form | Frozen liquid |
Storage | Store at -20°C/-80°C. Avoid freeze-thaw cycles. |
Introduction | Activation of the C1 complex is under control of the C1-inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein. |
Alternative Names | Serpin Family G Member 1; Plasma Protease C1 Inhibitor; C1IN; Serpin Peptidase Inhibitor, Clade G (C1 Inhibitor), Member 1; C1 Esterase Inhibitor; C1-Inhibiting Factor;C1-Inhibitor; C1INH; ; Serine/Cysteine Proteinase Inhibitor Clade G Member 1; Epididymis Secretory Sperm Binding Protein; Complement Component 1 Inhibitor; SERPING1; C1-INH; C1Inh |
Gene ID | 710 |
UniProt ID | P05155 |